Mitevski, Aleksandar and Pop Dimitrov, Aleksandar and Jankulovski, Nikola (2016) Primary diffuse large B cell lymphoma of the common bile duct:a case report and literature review. Journal of Disease and Global Health. ISSN 2454-1842
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Abstract
Non-Hodgkin lymphoma of the extra hepatic bile ducts is extremely rare, more often it is a result of a secondary
involvement in the systemic disease. In the Pub Med database we found only 7 reports presenting primary
diffuse large B cell lymphoma of the common bile duct.
We present a case of 56 years old male patient with an intramural lesion of the common bile duct that was found
while performing cholecystectomy for cholelithiasis. Consequently resection of the common bill duct with
Roux-en-Y hepaticojejunostomy was performed. The histopathology examination and Immunohistochemical
staining revealed primary diffuse large cell B lymphoma of the common bile duct. The patient was referred to an
oncology institution and was submitted to a combination chemotherapy using the R-CHOP protocol (Rituximab,
Cyclophosphamide, Hydroxydaunorubicin, Oncovin and Prednisone).
Primary lymphoma of the common bile duct is rare, but it should be considered as a differential diagnosis in
extra hepatic bile duct obstruction. The histopathology finding is usually obtained from a surgical specimen and
it is crucial for patients to receive adequate cancer therapy. Yet the best treatment modality is still to be defined.
| Item Type: | Article |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health sciences |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Aleksandar Mitevski |
| Date Deposited: | 28 Jan 2021 12:45 |
| Last Modified: | 28 Jan 2021 12:45 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/27034 |
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