Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data

Martin, John and Abubucker, Sahar and Heizer, Esley and Taylor, Christina M. and Mitreva, Makedonka (2010) Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data. Nucleic Acids Research, 40. D720-D728.

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Abstract

Nematode.net (http://nematode.net) has been a
publicly available resource for studying nema-
todes for over a decade. In the past 3 years, we
reorganized Nematode.net to provide more user-
friendly navigation through the site, a necessity
due to the explosion of data from next-generation
sequencing platforms. Organism-centric portals
containing dynamically generated data are available
for over 56 different nematode species. Next-
generation data has been added to the various
data-mining portals hosted, including NemaBLAST
and NemaBrowse. The NemaPath metabolic
pathway viewer builds associations using KOs,
rather than ECs to provide more accurate and fine-
grained descriptions of proteins. Two new features
for data analysis and comparative genomics have
been added to the site. NemaSNP enables the user
to perform population genetics studies in various
nematode populations using next-generation
sequencing data. HelmCoP (Helminth Control and
Prevention) as an independent component of
Nematode.net provides an integrated resource for
storage, annotation and comparative genomics
of helminth genomes to aid in learning more
about nematode genomes, as well as drug, pesti-
cide, vaccine and drug target discovery. With this
update, Nematode.net will continue to realize its
original goal to disseminate diverse bioinformatic
data sets and provide analysis tools to the broad
scientific community in a useful and user-friendly
manner.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Divisions: Faculty of Medical Science
Depositing User: Mirjana Kocaleva
Date Deposited: 30 Nov 2012 15:35
Last Modified: 30 Nov 2012 15:35
URI: https://eprints.ugd.edu.mk/id/eprint/2681

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