Nematode Gene Sequences: Update for December 2005

McCarter, James P. and Bird, David M. and Mitreva, Makedonka (2005) Nematode Gene Sequences: Update for December 2005. Journal of Nematology, 37 (4). pp. 417-421. ISSN 417–421

[thumbnail of Nematode Gene Sequences- Update for December 2005  1.pdf]
Nematode Gene Sequences- Update for December 2005 1.pdf

Download (80kB) | Preview


Molecular characterization of parasitic nematodes now relies heavily on information gained from genomic approaches. The avai l abi l i t y of t housands of new nucleotide sequences in searchable public databases ac-
celerates efforts to identify and characterize genes of interest, including those encoding pathogenicity factors, diagnostic markers, targets (for vaccines, drugs, or nemat i ci des ), and i mmunomodul at ory molecules .
Since 2000, we have provided periodic updates on the status of nematode sequencing projects of interest to the communities of researchers studying parasitic and free-living nematode biology (McCarter et al., 2000,
2002, 2003). Here we report on the availability of sequences from nematodes as of late 2005 and primarily cite literature from 2003–2005. Please see our 2003 update (McCarter et al., 2003) for a thorough listing of
the prior literature. 2003 to 2005, EST sequencing from mammalian para-
sites has slowed whereas EST generation from plant parasites has continued as the National Science Foundation (NSF)-funded collaboration between the GSC and North Carolina State University has been completed (Fig. 1). Sizable EST collections now exist for six Meloidogyne (root-knot nematode) species (Scholl and Bird, 2005), which is more than for any other nematode genus. ESTs have also been generated from three Tylenchida migratory endoparasitic species, the lesion nematodes Pratylenchus penetrans (Mitreva et al., 2004a)
and Pratylenchus vulnus, and the burrowing nematode Radopholus similis. A collection of more than 9,000 ESTs also is available from the dagger nematode Xiphinema index. Being a clade I Dorylaimia nematode, this repre-
sents the first EST collection from a non-Tylenchida

Item Type: Article
Subjects: Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Marija Kalejska
Date Deposited: 30 Nov 2012 14:11
Last Modified: 30 Oct 2014 13:46

Actions (login required)

View Item View Item