Use of antifibrinolytic mouthwash solution in anticoagulated oral surgery patients

Dimova, Cena and Evrosimovska, Biljana and Papakoca, Kiro and Georgiev, Zlatko and Angelovska, Bistra and Ristoska, Sonja (2012) Use of antifibrinolytic mouthwash solution in anticoagulated oral surgery patients. In: Macedonian Orthodontic Society, Second International Congress, 17-20 May 2012, Skopje.

[thumbnail of Abstract bookMOS2012.pdf] Text
Abstract bookMOS2012.pdf

Download (8MB)


Introduction:The ordinary treatment of anticoagulated patients includes the interruption of anticoagulant therapy for oral surgery interventions to prevent hemorrhage. However, this practice may logically increase the risk of a potentially life-threatening thromboembolism, so this issue is still controversial. The aim of the study was to evaluate the antifibrinolitic mouthwash solution (tranexamic acid) as a local haemostatic modality after oral surgery interventions. Methods:To realize the aim 100 individuals who received oral anticoagulants were included. Oral surgery interventions were performed with a reduction in the level of anticoagulant therapy in the first group. Oral surgery interventions were realized in the second group with no change in the level of anticoagulant therapy and with usage the tranexamic acid. After the interventions the surgical field was irrigated with a 5% solution of tranexamic acid in the treatment group whose oral anticoagulants had not been discontinued (second group) and with a placebo solution in the examined for whom the anticoagulant therapy was reduced (first group). Patients were instructed to rinse their mouths with 10 ml of the assigned solution. Results:The analysis showed that there was no significant difference between the two treatment groups in the bleeding incidence after oral surgery interventions. Conclusion: The anticoagulant treatment does not need to be withdrawn before the oral surgery provided that the local antifibrinolytic therapy is instituted.

Item Type: Conference or Workshop Item (Poster)
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Cena Dimova
Date Deposited: 27 Nov 2012 12:23
Last Modified: 30 Sep 2013 13:36

Actions (login required)

View Item View Item