Boschi, Alessandra and Martini, Petra and Janevik-Ivanovska, Emilija and Duatti, Adriano (2018) The emerging role of copper-64 radiopharmaceuticals as cancer theranostics. Drug Discovery Today, 23 (8). pp. 1489-1501. ISSN 1359-6446
![]() |
Text (The emerging role of copper-64 radiopharmaceuticals as cancer theranostics)
S135964461730510X - Published Version Download (78kB) |
Abstract
Copper radionuclides are rapidly emerging as potential diagnostic and therapeutic tools in oncology, particularly 64Cu-radiopharmaceuticals for targeting neuroendocrine, prostate, and hypoxic tumors. Unexpectedly, experimental results are also revealing the impressive biological behavior of simple [64Cu2+] ions. For example, it has been demonstrated that administration of ionic [64Cu2+] in physiological solution allows the selective targeting of a variety of malignancies. These remarkable biological properties appear to be crucially linked to the natural role of copper ions in cell proliferation. Here, we review the current status of 64Cu-radiopharmaceuticals in molecular imaging and cancer therapy.
Item Type: | Article |
---|---|
Additional Information: | additional contact person Adriano Duatti dta@unfe.it |
Subjects: | Medical and Health Sciences > Basic medicine Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health biotechnology |
Divisions: | Faculty of Medical Science |
Depositing User: | Emilija Janevik |
Date Deposited: | 13 Aug 2018 09:45 |
Last Modified: | 13 Aug 2018 09:45 |
URI: | https://eprints.ugd.edu.mk/id/eprint/20288 |
Actions (login required)
![]() |
View Item |