The role of hemodialysis in treatment of acute acetic acid poisonings

Chibishev, Andon (2017) The role of hemodialysis in treatment of acute acetic acid poisonings. The International Journal of Artifical Organs, 40(5) (219-22). ISSN 0391-3988

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Abstract

Introduction: The aim of this study is to show the importance of hemodialysis as an active method in treatment
of acute acetic acid poisonings. Its main role is to support the renal function during the state of the intoxication
when patients develop acute renal failure.
Methods: We analyzed data from a 10-year period, a total of 71 patients who ingested acetic acid, either intentionally
or accidentally. Patients with a need of hemodialysis (HD) treatment underwent 3- to 4-hour HD sessions
every day or every second day, according to clinical assessment, as needed, until recovery of kidney function.
Results: In the period between 2006 and 2015 at the university clinic for toxicology and urgent internal medicine,
we hospitalized 6,106 patients with different kinds of intoxication, of which 1.162% ingested concentrated
acetic acid; 47 patients were female and 24 were male. The minimal age of patients was 18 and the maximal
74 years. A total of 28 (39.43%) of the patients developed acute renal failure and in 10 patients (14.08%) we used
hemodialysis as a part of the treatment. The maximum number of performed sessions in one patient was five
and the minimal number of performed sessions in one patents was only one session. The use of heparin led to
fatal bleeding in 4 patients. The mortality rate was 7% and most of the cases resulted in fatalities during the first
96 hours after ingestion.
Conclusions: Acetic acid poisonings are one of the most dangerous intoxications seen in clinical toxicology. The
use of hemodialysis in some of the patients who develop acute renal failure can be of great importance and it
should be put into official treatment protocols due to its great number of advantages in renal function support.
Keywords: Acetic acid, Hemodialysis, Intoxication, Renal function

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Andon Cibisev
Date Deposited: 28 Feb 2019 07:53
Last Modified: 28 Feb 2019 07:53
URI: https://eprints.ugd.edu.mk/id/eprint/19245

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