Nutritional therapy in the treatment of acute corrosive intoxication in adults

Chibishev, Andon and Markovski, Velo and Smokovski, Ivica and Shikole, Emilija and Stevcevska, Aleksandra (2016) Nutritional therapy in the treatment of acute corrosive intoxication in adults. Nutritional Therapy, 28 (1). pp. 66-70.

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Introduction: Acute intoxications with corrosive substances can cause severe chemical injuries of the upper gastrointestinal
tract, most often located in the mouth, pharynx, esophagus, stomach and duodenum. If a patient survives the acute phase
of intoxication, regenerative response may result in esophageal and/or gastric stenosis, and increased risk of esophageal and
gastric cancer. Such intoxication may be fatal due to perforation or tracheal necrosis. Enteral nutrition is a nutritional method
when nutritional substances are administered through specially designed tubing placed through the nose or percutaneously,
directly into the GIT. Aim: The aim of this study is to describe the methods of artificial nutrition in patients with acute corrosive
intoxications and the importance of nutritional support in the treatment of these intoxications. Discussion: Nutrition in
the treatment of acute corrosive intoxications is one of the most important therapeutic processes that largely contribute to
faster recovery of the post-corrosive injuries of upper GIT, stabilization of biologic, immunologic and metabolic parameters,
and reduction of length of stay in hospital Aim of the treatment of acute corrosive intoxications is to prevent perforation and
progressive fibrosis, and esophageal and gastric stenosis. There are different and often conflicting positions, on the conservative
treatment of acute corrosive intoxications in adults. Such treatment mainly consists of anti-secretory treatment, antibiotics and
intensive hyper-alimentation, aiming to prevent late post-corrosive intoxications. Conclusion: It is considered that nutritional
support plays a major role in maintenance of metabolic processes and prevention of severe metabolic complications that could
additionally aggravate the condition and impair the treatment.

Item Type: Article
Uncontrolled Keywords: corrosive poisonings, deglutition, deglutition disorders, nutritional therapy, enteral nutrition, parenteral nutrition
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Dance Vasileva
Date Deposited: 31 Jan 2017 12:17
Last Modified: 31 Jan 2017 12:17

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