Vavlukis, Marija (2016) Are diabetes mellitus and lipoprotein(a) independently or causally associated with an increased cardiovascular risk? The Anatolian Journal of Cardiology, 16 (12). ISSN 21492263 (In Press)
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Abstract
Serum Lp(a) and diabetes mellitus increase the risk of cardiovascular diseases (CVD). However, the relationship between serum Lp(a) and diabetes is poorly characterized, and it is a subject of debate as to whether they are independently or causally associated (1).
One of the atherogenic mechanisms in hyperglycemia is
based on enhanced inflammation. Diabetes is associated with
increased vascular production of reactive oxygen species (ROS),which causes premature cell apoptosis via reduction of endothelial nitric oxide (NO), resulting in decreased smooth muscle relaxation and antiatherogenic properties, including decreased platelet aggregation and adhesion inhibition (1).
| Item Type: | Article |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Marija Vavlukis |
| Date Deposited: | 14 Mar 2017 12:07 |
| Last Modified: | 14 Mar 2017 12:07 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/16774 |
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