Iron deficiency in repeated blood donors in WU transffusiology at General Hospital in Stip

Vitlarova, Jordanka and Kamcev, Nikola and Kamceva, Gordana and Velickova, Nevenka (2009) Iron deficiency in repeated blood donors in WU transffusiology at General Hospital in Stip. Vox Sanguinis, 96 (1). p. 138. ISSN 1423-0410

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Abstract

Aims: To evaluate latent iron insufitietion in blood donors who have donored from 400-450ml blood in the last five years, four times a year in male donors, i.e three times a year female donors.
Methods: In the W.U Transfusiology, before each donation it is obligatory to determine the value of hemoglobin and hematocrit. Female standard values of hemoglobin are >12g/dl and hematocrit 38%and the male standard values are >13g/dl and hematocrit 40%.In blood donors with limited values of hemoglobin and hematocrit, blood samples of satelite bags were taken during the process od phlebotomy and the same were sent to additional lab-biochemical measurements of iron status in the Central clinic biochemical laboratory.
Results: In 2007 there was 4008 voluntary blood donors at the age of 18 to 65, i.e 2580 males (64.37%) and 1428 (35, 62%) females. From the total number of repeated blood donors, 3540 (88.32%) were repeated ones, and only 468 (11.68%) were first time donors. From the total number of repeated blood donors, 553 (15,62%) were femeles who regulary donated blood for four times in the last five years and 328 (9,26%) were females who donated blood for three times in the same period. 5 (0,90%)males or 7 (2.13%)females of these, were with low values of hemoglobin and hematocrit, for which reason they were refused to donor blood. In 42 (7.59%) males and 61 (18.58%) females limited values of hemoglobin and hematocrit were found out for which additional lab-biochemical measurements of iron status were made. And, it was evaluated that there was low concentration of serum iron, less than 7μmol/l, low concentration of serum feritin, less than 10mg/l, and increased values of total iron-binding capacity over 72 μmol/l.
Conclusion: The obtained results show that uncontrolled repeated blood donation is a possible risk factor for the appearance of iron deficient anemia, especially in females. To avoid the possible side effects, before each blood donation additional lab-biochemical measurements are necessary which show the existance of latent iron deficiency or iron-defficient anaemia.

Item Type:	Article
Subjects:	Medical and Health Sciences > Basic medicine Medical and Health Sciences > Health sciences
Divisions:	Faculty of Medical Science
Depositing User:	Nevenka Velickova
Date Deposited:	27 Nov 2012 10:09
Last Modified:	27 Nov 2012 10:09
URI:	https://eprints.ugd.edu.mk/id/eprint/1506

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