Popovska, Mirjana and Radojkova-Nikolovska, Vera and Minovska, Ana and Muratovska, Ilijana and Mijovska, Aneta (2015) Etiopathogenetic Cellular Mechanisms in Oral Lichen Planus. International Journal of Science and Research (IJSR), 4 (11). pp. 1985-1989. ISSN 2319-7064
Preview |
Text
MIRA TRUD SO IF (1) (1).pdf Download (1MB) | Preview |
Abstract
Abstract: Objective: to follow the immune status in patients with oral lichen planus (OLP), by assessing the level of T and B
lymphocytes in the blood. Material and method: 54 patients with OLP and 50 healthy people were examined. Experimental group was
divided into three subgroups: reticular, erythema-exudative and bullоus form. Both groups, control and experimental, were assessed for
values of T and B lymphocytes in the blood in the Institute for Transfusion. Findings were statistically processed using the Student-t
test. Results: In the phase of exacerbation in all three clinical forms of OLP, T and B cells in peripheral blood were increased, versus
the control group (p<0.001). In the phase of remission in reticular, erythema-exudative and bullous form, slight decrease in the values
of T and B cells was observed, but it was still above control values and with high significance (p<0.001), except for B lymphocytes in
the reticular form where p <0.01. Conclusion: The increased values of T and B lymphocytes in the phase of exacerbation and
remission, are explained with the chronicity of the process, which leads us to the conclusion that the immune system is reconstructed in
terms of increased cell activity.
| Item Type: | Article |
|---|---|
| Subjects: | Medical and Health Sciences > Basic medicine Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health sciences Medical and Health Sciences > Other medical sciences |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Ana Minovska |
| Date Deposited: | 24 Dec 2015 09:30 |
| Last Modified: | 24 Dec 2015 09:30 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/14700 |
Actions (login required)
 |
View Item |