Georgiev, Antonio and Smokovski, Ivica and Pavlovska, Kristina and Georgieva, Daniela (2009) Use of Framingham model for identifying type 2 diabetes patients for primary prevention of coronary artery disease with statin treatment. Medicus, 12 (2). pp. 18-21. ISSN 1409-6366
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Abstract
Objective: To determine the number of type 2 diabetic patients identified for primary prevention of Coronary Artery Disease (CAD) with statins by Framingham model for calculation of 10-year CAD absolute risk. Material and methods: Observational, cross-sectional study including 516 type 2 diabetic patients with no arterial disease (CAD, cerebrovascular disease or peripheral arterial disease), no prior hypolipaemic treatment, aged 30-65 years, receiving insulin treatment for 6 months. Patients were identified for primary prevention of CAD with statins if 10-year CAD absolute risk was higher than 15% as assessed by Framingham model and total cholesterol higher than 5.0 mmol/l. Results: Out of 516 patients, mean 10-year absolute risk for CAD as assessed by Framingham model was 16.8 ± 8.6%, and 232 patients (45.0%) were identified with 10-year CAD absolute risk >15% and total cholesterol >5.0 mmol/l. Conclusion: Use of Framingham model identifies cosiderable number of type 2 diabetic patients with no primary prevention in whom such pevention of CAD with statins is required, having both clinical and health economics implications. Key words: Framingham, diabetes type 2, primary
| Item Type: | Article |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine Medical and Health Sciences > Health sciences Medical and Health Sciences > Other medical sciences |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Ivica Smokovski |
| Date Deposited: | 28 Dec 2015 11:33 |
| Last Modified: | 28 Dec 2015 11:33 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/14620 |
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