Issuing the antibiotics for children in pharmacies in Republic of Macedonia

Angelovska, Bistra and Drakalska, Elena and Atanasova, Marija and Kostik, Vesna and Trajkoska, Jasmina (2015) Issuing the antibiotics for children in pharmacies in Republic of Macedonia. In: Treći kongres farmaceuta Bosne i Hercegovine sa međunarodnim učešćem, 14-17 May, 2015, Saraevo, BIH.

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Abstract

The use of medicines for infants and children is presenting one unique set of challenges, because children are the most vulnerable population in any society. In contrast to adults, absorption, distribution, metabolism and excretion of drugs in infants and children can be very different. The aim of this study is to present the characteristics and classification of antibiotics recommended for children, according to WHO, EMA and MWD, pediatric dosage forms registered in Republic of Macedonia and also the most prescribed antibiotics for children in 2013 in Republic of Macedonia compared with standard treatment methods.
Materials and methods: Data analysis of the most prescribed antibiotics covered by the Fund for children in 2013 in Republic of Macedonia according to the number of prescribed recipes compared with the recommendations of WHO, EMA and MWD.
Results: The obtained results from the performed research showed that the most commonly prescribed antibiotic in 2013 is amoxicillin with clavulanic acid (875 mg + 125 mg) in form of tablet, with 280 863 prescribed recipes. Ciprofloxacin 500 mg tablet is represented with slightly fewer prescriptions 209 603, while the prescribed recipes for amoxicillin with clavulanic acid suspension is 130 961. Other antibiotics covered by the Fund, object of this study, are represented with number of prescribed recipes in range of 1200- 100 000.
Conclusion: According to the obtained results, the most prescribed pediatric antibiotic in 2013 is amoxicillin with clavulanic acid (875 mg + 125 mg) in form of tablet, with 280 863 prescribed recipes, which corresponds to recommendations of MWD. In contrast the second most prescribed antibiotic Ciprofloxacin is not recommended according to WHO. Despite the regulation in Republic of Macedonia, self- medication has a relatively high percentage due to the availability of antibiotics without prescription and their inappropriate use, general lack of knowledge about mechanism of action of antibiotics, side effects and the emergence of resistance.

Item Type: Conference or Workshop Item (Poster)
Subjects: Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Elena Drakalska Sersemova
Date Deposited: 22 May 2015 14:18
Last Modified: 22 May 2015 14:18
URI: https://eprints.ugd.edu.mk/id/eprint/13184

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