Immunocompromised patients with shingles - Therapeutic approach

Zabaznoska, L. and Ilieva, L. and Markovski, Velo and Semenakova-Cvetkovska, V. (2010) Immunocompromised patients with shingles - Therapeutic approach. International Journal of Infectious Diseases, 14. e477. ISSN 12019712

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The complexity of the therapeutic approach
of the immunocompromised patients is determinate by
the capacity of their immunoresponse corresponding with
the arising infection. Among the patients with shingles
with a comorbide immunodeficiency syndrome such as primary
hypogamaglobulinaemia or secondary lymphopenia as
a result of a long lasting immunosuppressive therapeutic
treatment that is even more complex, due to threatening
viral generalization, including visceral generalization of theillness as well as dermal and pulmonary bacterial superinfection.
Methods: During the 6 year long period, 20 immunocompromised
patients with shingles were hospitalized and
healed in our department. Dermal eruptions were spreaded
on several dermatoms, in 8 patients with dermal generalization.
Visceral generalization appeared in 4 cases with all
consecutive disorders. Diagnostic criteria, including complete
blood count (CBC), sedimentation, chemistry profile
of renal and liver function tests, bacteriological (inducted
expectorated) sputum sample testing, blood culture, pleural
fluid analysis, chest xray and tomography, were determining
moments in the diagnostic procedure and therapeutic

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Rubin Gulaboski
Date Deposited: 13 Mar 2015 15:02
Last Modified: 13 Mar 2015 15:02

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