CNS disorders induced by radiation therapy of the brain

Simeonovska Joveva, Elena and Karakolevska Ilova, Marija (2014) CNS disorders induced by radiation therapy of the brain. European Journal of Neurology: Abstracts of the Joint Congress of European Neurology, Istanbul, Turkey, May 2014, 21 (6). pp. 388-713. ISSN 1468-1331

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CNS radiation therapy is commonly used to treat a variety of CNS tumors including primary and metastatic tumors of the brain or prophylactically in an attempt to prevent the development of metastases like in small cell lung cancer. The treatment dose and volume depend on the histology, location, and size of the tumor and sometimes radiation administered to treat CNS neoplasms can result in a variety of acute, subacute, and delayed clinical syndromes of the brain of which the most important in clinical practice is radionecrosis witch is irreversible and occurs 1 to 3 years after radiation and the neurologic symptoms depend on the location and size of necrotic lesion. These disorders are important because their presentation can mimic tumor recurrence. Cerebral radiation necrosis often occurs after focal EBRT or brachytherapy and it is very uncommon after WBRT.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Elena Joveva
Date Deposited: 11 Jun 2014 12:33
Last Modified: 11 Jun 2014 12:33

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