Formulation and characterization of nanosized carriers as potential platforms for topical delivery of antioxidants

Drakalska, Elena and Angelovska, Bistra and Sterjova, Marija and Cvetkovski, Aleksandar (2018) Formulation and characterization of nanosized carriers as potential platforms for topical delivery of antioxidants. In: VII Serbian Congress of Pharmacy with international participation, 10-14 Oct 2018, Belgrade, Serbia.

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Abstract

Skin is protected from the harmful effects of free radicals by the presence of an endogenous antioxidant system. However, when exposed to ultraviolet (UV) radiation, there is an imbalance between pro-oxidants and antioxidants, leading to oxidative stress and photoaging of the skin. In order to prevent skin aging, use of topical antioxidants in different formulations is method of choice in pharmaceutical industry. However, many bioactive substances are unstable when exposed to light, lose activity during storage and possess low solubility and bioavailability. The aim of this study is to present the advantages of incorporation of antioxidants into nanocarriers such as niosomes, liposomes and nanoemulsions as an intriguing strategy to overcome listed limitations of antioxidants.

Item Type: Conference or Workshop Item (Poster)
Subjects: Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Elena Drakalska
Date Deposited: 19 Oct 2018 08:11
Last Modified: 19 Oct 2018 08:11
URI: http://eprints.ugd.edu.mk/id/eprint/20613

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