The Liver Parameters In The Collagen-Induced Arthritis Rat Model

Spasov, Mire and Gjorgoski, Icko and Hadzi-Petrusev, Nikola and Spasova, Verica (2014) The Liver Parameters In The Collagen-Induced Arthritis Rat Model. Wulfenia Journal, 21 (4). ISSN 1561-882X

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Abstract

The living organisms use defensive mechanisms in their struggle to keep the inner homeostasis and potect themselves from the changes induced by external factors and penetrative agents. The manifestation of these changes depends on the character, the intensity and the duration of the agents’ activity, and on the physiological characteristics of the organism (gender, age, health condition etc.). The aim of our study was to analyze, the effects of collagen-induced arthritis (that is, the autoimmune reaction and the inflammation) on some liver parameters. We determined the content of proteins, DNA and RNA. Animals with collagen-induced arthritis showed decreased relative content of proteins in liver, compared to controls. On the contrary, the relative content of DNA and RNA were increased in animals treated with collagen. Кеywords: rheumatoid arthritis, collagen-induced arthritis, inflamation, Wistar rats, proteins, DNA, RNA, serum. Introduction:

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Divisions: Faculty of Medical Science
Depositing User: Mire Spasov
Date Deposited: 06 May 2014 09:42
Last Modified: 06 May 2014 13:35
URI: http://eprints.ugd.edu.mk/id/eprint/9890

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