Comparative examination of the speed of release of Pyridoxin HCL of vitamin B6 tablets á 20 mg

Pavlovska, Gorica and Darkovska-Serafimovska, Marija and Nestorovska-Gjosevska, Biljana (2011) Comparative examination of the speed of release of Pyridoxin HCL of vitamin B6 tablets á 20 mg. In: 2nd International Congress, Engineering, Ecology and Materials in the Processing Industry, 2011, Jahorina.

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Abstract

Of commercial reasons, Vitamin B6 20 mg tablets which are produced in Radovis were needed to be produced in Skopje. In order to get licenses for the production of the new location was necessary to carry out a confirmation of the existing by technology. To this end was made comparison to the more parameters (appearance, weight, strength, dimensions, fragility, disintegration, contents, uniformity of content and solubility) of tablets produced in both locations. In order to confirm the technology was needed to compare the solubility of the two products in three different media (0.1 M HCl with pH=1.2, acetate buffer with pH=4.5 and phosphate buffer with pH=6.8). Liberation of HCl was monitored pyridoxine in 12 tablets of the old site and 12 tablets of the new location, in three intervals of Solubility of tablets in all three media. It is made statistical processing of the received data confirming the transfer of technology.

Item Type: Conference or Workshop Item (Poster)
Subjects: Engineering and Technology > Medical engineering
Divisions: Faculty of Medical Science
Depositing User: Marija Darkovska-Serafimovska
Date Deposited: 24 Oct 2013 08:13
Last Modified: 24 Oct 2013 08:13
URI: http://eprints.ugd.edu.mk/id/eprint/7700

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