Protective role of vitamins E and C in carbon tetrachloride induced acute liver damage

Hadzi-Petrusev, Nikola and Mladenov, Mitko and Davceva, Olivera and Sterjovska-Aleksovska, Andrijana and Spasov, Mire and Dodevska, D and Stojchevska, E and Gjorgoski, Icko (2009) Protective role of vitamins E and C in carbon tetrachloride induced acute liver damage. Balkan Journal of Clinical Laboratory. ISSN 1310-4543

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Abstract

The CCL4 hepatotoxic impact is achieved when it is activated to from highly reactive radicals, which have various effects; initiation of lipid peroxidation being probably the most important one. The toxic outcome may be prevented through use of antioxidants; vitamin E presenting the first line of defence. Keeping the concentration of reduced vitamin E,requires a network of other antioxidants that can reduce the radical from of vitamin E to its native from. Vitamin C is an antioxidant that is able to reduce vitamin E directly.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Divisions: Faculty of Medical Science
Depositing User: Mire Spasov
Date Deposited: 09 May 2013 12:52
Last Modified: 09 May 2013 12:52
URI: http://eprints.ugd.edu.mk/id/eprint/6218

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