Physicochemical basis for the microbicidal action of disinfection solutions. I. Polyvinylpyrrolidinone-iodine

Gjorgjeska, Biljana (1990) Physicochemical basis for the microbicidal action of disinfection solutions. I. Polyvinylpyrrolidinone-iodine. International Journal of Pharmaceutics, 65 (28). pp. 35-41. ISSN 0378 - 5173

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Abstract

A new potency coefficient, termed the disinfectant activity coefficient of solution (DACS), for aqueous polyvinylpyrrolidinoneiodine (PVP-iodine) solutions is proposed. The DACS index, which is the sum of four terms (fluidity, surface tension, redox potential and osmolality), results in good correlation with the germicidal activity at different dilutions of PVP-iodine. Factor statistical analysis was applied to all the terms; the first two factors account for over 96% of the total variation in the data set (factor 1, 71.7%; factor 2, 24.5%). Keywords Polyvinylpyrrolidinone-iodine; Viscosity; Fluidity; Surface tension; Osmolality; Redox potential; Disinfection activity; Staphylococcus aureus

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Natural sciences > Biological sciences
Natural sciences > Chemical sciences
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health biotechnology
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Biljana Gorgeska
Date Deposited: 29 Apr 2013 12:27
Last Modified: 03 Jun 2013 07:43
URI: http://eprints.ugd.edu.mk/id/eprint/6179

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