Venostasis test as a method of choice to evaluate blood fibrinolytic capacity during third molar surgery

Dimova, Cena and Evrosimovska, Biljana and Kovacevska, Ivona (2012) Venostasis test as a method of choice to evaluate blood fibrinolytic capacity during third molar surgery. Contributions, 33 (2). pp. 205-207. ISSN 0351-3254


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The aim of our research evaluates the fibrinolytic capacity during the oral surgical interventions – operative extraction of semi impacted third molars having caused activity of blood fibrinolysis. Having intention to establish the condition of the blood vessels endothelium before the oral surgical interventions, the influence of the surgical procedures upon the endothelium, as well as the response of the endothelium after the interventions, the test of venostasis (venous stasis) was conducted in all subjects. This test measures the global fibrinolytic activity of the plasma, caused by anoxia. In order to realize the aim, first blood sample was taken before the beginning of the test, and then the indicated oral surgical intervention was performed. Immediately, after the completion of the surgery, the test of venostasis was carried out lasting for five minutes and right after the test, second sample of blood was taken. Using the method of fibrin plates, the level of the activators and inhibitors of the plasminogen was established after wards. The average values of the pro activators and inhibitors of fibrinolysis from the venostasis test, in all subjects have shown increased values compared to the same ones in the control group, in all researched relations. Statistically, a significant difference has been established after performed interventions. These findings support the fact of possible damage of the blood vessels endothelium and change of the fibrinolytic capacity in the perioperative period of third molar surgery. Key words: third molar impaction, oral surgery, fibrinolytic system, stress.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Cena Dimova
Date Deposited: 06 Mar 2013 10:37
Last Modified: 19 Feb 2014 08:39

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