Truncus arterious communis (TAC) associated with malformations of other organ systems

Sokolovska-Malovcheva, Gabriela and Duganovska, Snezana and Janevska, Vesna and Serafimov, Aleksandar and Komina, Selim (2011) Truncus arterious communis (TAC) associated with malformations of other organ systems. 1st Macedonian Congress of Pathology with International Participation, Ohrid, Macedonia, 1 (1). pp. 71-75.


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Truncus arteriosus communis (TAC) is a rare congenital cardiopathy where a common blood vessel comes out of the base of the heart just like a major artery that supplies the coronary, pulmonary and systemic circulation. The anomaly is thought to result from incomplete or failed septation of the embryonic truncus arteriosus. MATERIALS AND METHODS At the Institute of Pathological Anatomy at the Medical Faculty, which is a part of UKIM, in the period from 2007 to 2010, 1739 autopsies were made and in 70 cases complex congenital cardiopathies were diagnosed . Using a profound morphological analysis , five cases with TAC were separate, three of which were fetuses with induced abortion, because the clinical diagnosis Cardiopathia congenital was set, and two lived do 2,5 months. Two of them were female, and three male. RESULTS In the analysis of TAC a Collett & Edwards schematic representation and classification is used with the following variations of TAC type II (5), in one case there are 4 valves located at the ostium, and in another case the right pulmonary artery comes out while the left is missing . The deeper morphological analysis showed accompanying heart defects and VSD in all five cases of TAC. By A-V channel they are found at (1), HLHS (2), EFE (1) and LHSVP (1). The pathoanatomic analysis of the other organic systems of the TAC cases is combined with severe anomalies of other systems in 4 cases:1. TAC +hydrocephalus internus+ omphalocoelae + hypoplasio extremitas superioris+syndactilia + agenesio pulmonum sin (1), 2.TAC + pulmo unilobatum bill. +hypoplasio thimy+ ren polycysticus (1), 3.TAC +thymomegalia+ agenesio renum + cheilognathopalathoshisis + hexodactilia mani bill. + arrhinia (1)4. TAC + pulmo dexter billobatum + lien accesorius+pes equinovarus bill (1). CONCLUSION The deepened morphological analysis showed that the most common type of TAC is a type II according to Collett & Edwards classification, with mild male predominance (3:2) and a high percentage (80%) of association with malformations of other organ systems. The knowledge of the morphology TAC and its connection to other anomalies is very important for understanding and early detection of this congenital cardiopathy which enables well-timed and successful further surgical treatment.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Natural sciences > Biological sciences
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health sciences
Divisions: Faculty of Medical Science
Depositing User: Aleksandar Serafimov
Date Deposited: 28 Jan 2013 12:57
Last Modified: 28 Jan 2013 12:57

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