Cytochrome P450 or high pH induce structural and functional changes of Coenzyme Q10

Gulaboski, Rubin and Bogeski, Ivan and Mirceski, Valentin and Reinhard, Kappl and Hoth, Markus (2010) Cytochrome P450 or high pH induce structural and functional changes of Coenzyme Q10. In: Swiss Gordon Conference 2010, NOXes.

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Abstract

Coenzyme Q10 is a lipid soluble compound indispensable for optimal functioning of all living organisms, and it is the only non-protein in the mitochondrial electron transfer chain. Using voltammetry, UV-VIS spectrophotometry, EPR and NMR we have shown that Cytochrome P450 and high pH's induce structural and functional changes in Coenzyme Q10. The new derivative has much greater antioxidative potential and ability to bind Ca2+ and other earth-alkaline cations.

Item Type: Conference or Workshop Item (Speech)
Subjects: Medical and Health Sciences > Basic medicine
Natural sciences > Chemical sciences
Divisions: Faculty of Agriculture
Depositing User: Rubin Gulaboski
Date Deposited: 17 Dec 2012 13:21
Last Modified: 20 Dec 2012 10:38
URI: http://eprints.ugd.edu.mk/id/eprint/3715

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