Underlying cause of neonatal macrosomia

Zisovska, Elizabeta and Kalcev, Goce (2020) Underlying cause of neonatal macrosomia. In: Online maternal health conference. Minding Mothers with Morbidities II, 29 Oct 2020, Dublin, Ireland.

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Abstract

Background: High blood sugar levels (BSL) in pregnant could be a reason for macrosomia. The aim
of our study was to present some indicators in LGA babies related to maternal diabetes.
Methods: This was a cohort prospective study conducted in the first six months in 2020 at the
University Clinic for Gynecology and Obstetrics in Skopje, North Macedonia. The identification of
the LGA newborns was according to WHO growth standards for both sexes.
Results: 108 LGA newborns, divided into three groups: A-36 LGA babies (33,3%) whose mothers
had no history of Diabetes; B-14 LGA babies (12,9%) of mothers with pre-gestational Diabetes; C-56
LGA babies (51,6%) of mothers with Gestational diabetes were examined. Glycaemia was taken
according to the National Guidelines (30 minutes after the second feed). The results showed
significantly lower BSL in group C, mean 1,6±0,2 mmol/L (OR 2.19, 95% CI, 1.25–3.82, P=0.01). Both
groups of newborns (A and B) had no significant difference in the mean value of BSL. The ratio of
male/female was significantly higher in group A (1,4) compared to the other two groups, suggesting
that associated factors other than diabetes are responsible for the macrosomia. The results showed
that LGA babies have a much higher risk if their mothers have gestational diabetes compared to
pre-existing diabetes, or with those whose mothers had no history or parameters of diabetes.
Conclusion: The impact of gestational diabetes during pregnancy depends on early identification
and good management.

Item Type: Conference or Workshop Item (Poster)
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Elizabeta Zisovska
Date Deposited: 12 Nov 2020 10:42
Last Modified: 12 Nov 2020 10:42
URI: https://eprints.ugd.edu.mk/id/eprint/26722

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