Detection of HBsAg and HCV antibodies at i.v drug users

Kamcev, Nikola and Vitlarova, Jordanka and Kamceva, Milka (2002) Detection of HBsAg and HCV antibodies at i.v drug users. 10th Internacional Congress of Infectious Diseases, Singapore, 11-14 March, 2002.

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Abstract

Background. Prevailing of HCV antibodies at intravenous drug addicts according to certain examinations in USA and Europe is 70-92%. Around 40% of intravenous drug users in the period of 4 years become HCV antibodies positive and in the period of 10 years almost 100%. According to Kelen GD and collaborators prevailing of HBsAg at intravenous drug addicts is 6%. Aim of the work. Prevailing of HCV antibodies and HBsAg at drug addicts in the district of Stip to be determined. Methods. In the past few years in the W.U Transfuziology in Medical Center in Stip 48 intravenous drug addicts are serologicaly tested for detection of anti HCV and HBsAg. All the 48 examinated have used the drugs for more than 5 years. 43 (89.5%) of them are man and 5 (10.4%) are women. They are all young people and born after 1977. For detection of HBsAg in the serum samples of the intravenous drug users microelisa test Hepanostika HBsAg UNI-FORM II of the firm Organon tehnika, United Biomedical, Inc.New York – USA is used. For detection of HCV antibodies in the serum samples UBI HCV EIA 4.0 of the firm Organon tehnika United Biomedical, Inc.New York – USA is used. As confirmed test for HBsAg Hepanostika Uni-Form Confirmation (Organon tehnika) is used; and for anti HCV Lia Tek HCV III; Organon tehnika, United Biomedical, Inc.New York – USA is used. Results.From 48 drug users serologicaly tested for presence of anti HCV and HBsAg it is determined: the presence of anti HCV at 44 (91.66%); the presence of HCV and HBsAg at the same time at 3 (6.25%); and presence of only HBsAg at 1% (2.08%). Conclusion.The results of our examinations show that the prevailing of anti HCV antibodies in comparison with the prevailing of HBsAg at intravenous drug users in the district of Stip is high and dominant.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Nikola Kamcev
Date Deposited: 13 Jan 2020 09:34
Last Modified: 13 Jan 2020 09:34
URI: http://eprints.ugd.edu.mk/id/eprint/23230

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