Kalcev, Goce and Zisovska, Elizabeta (2019) Visceral leishmaniasis in a patient with aortic coronary bypass transplant and hepatitis case report. International Journal Of Creative and Innovative Research In All Studies, 1 (12). pp. 1-3. ISSN 2581-5334
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Abstract
Aims: Visceral leishmaniasis (cala-azar) caused by
the protozoal parasite Leishmania donovani, is one
of the major causes of worldwide morbidity and
mortality. In this case report, we present a female
patient, who had been diagnosed with Visceral
Leishmaniasis.
Case report: A 56-year-old woman from Skopje,
Republic of Macedonia, who was in Barcelona and
Istanbul a year ago, was taken to the state hospital
because of fever and hepatosplenomegaly. The
diagnosis is made with bone marrow biopsy. The
patient had previously an aortic coronary bypass
transplant. During the stay of the Intensive Care and
Therapy Department at the Clinic for Infectious
Diseases and Febrile Conditions in Skopje, Hepatitis
C virus has been laboratory diagnosed.
Unfortunately, the patient ended with death.
Conclusion: We hope that with the presentation of
this case, we will increase the need for further
exploration of geographical changes,
epidemiological characteristics and interconnections
between leishmania parasites.
Keyword: leishmaniasis, protozoa, Hepatitis C
1.INTRODUCTION
Visceral leishmaniasis (cala-azar) caused by the
protozoal parasite Leishmania donovani, is one of the
major causes of worldwide morbidity and mortality (1).
Leishmaniasis is an inflammatory, chronic disease that
affects the skin, mucous membranes and visceral
organs, caused by intracellular parasites that are
transmitted by infected sand flies of the genus
Flebotomus. The life cycle of Leishmania takes place in
two phases, the promastigote which lives extracellularly
in the infected phlebotomes and the amastigote, which
lives and reproduces intracellularly in the host's
reticuloendothelial cells (2). Mammals, including foxes,
rodents and dogs are infection reservoirs (3). The
amastigotes from Leishmania species have a particular
affinity for replication in the liver, spleen, bone marrow
and lymph nodes causing fatal lesions. (4). We present a
complex case of a 56 year old woman from Skopje,
Republic of Macedonia with three independent types of
morbidities, as follows: aortic coronary bypass
transplant, Hepatitis C and visceral leishmaniasis.
2.CASE REPORT
56-year old woman from Skopje, Republic of Macedonia
of Albanian nationality was referred to University Clinic
for Infectious Diseases and Febrile conditions in Skopje
for management of visceral leishmaniasis. This patient
10 years ago was admitted to the Clinic “Filip II” because
of a heart attack. An aortic coronary bypass transplant
was made. She regularly went to controls for the
examination of cardiac function and control of current
therapy. She has been advised on several occasions t
| Item Type: | Article |
|---|---|
| Subjects: | Medical and Health Sciences > Clinical medicine |
| Divisions: | Faculty of Medical Science |
| Depositing User: | Elizabeta Zisovska |
| Date Deposited: | 13 May 2019 13:10 |
| Last Modified: | 13 May 2019 13:10 |
| URI: | https://eprints.ugd.edu.mk/id/eprint/22024 |
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