Visceral leishmaniasis in a patient with aortic coronary bypass transplant and hepatitis case report

Kalcev, Goce and Zisovska, Elizabeta (2019) Visceral leishmaniasis in a patient with aortic coronary bypass transplant and hepatitis case report. International Journal Of Creative and Innovative Research In All Studies, 1 (12). pp. 1-3. ISSN 2581-5334

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Abstract

Aims: Visceral leishmaniasis (cala-azar) caused by the protozoal parasite Leishmania donovani, is one of the major causes of worldwide morbidity and mortality. In this case report, we present a female patient, who had been diagnosed with Visceral Leishmaniasis. Case report: A 56-year-old woman from Skopje, Republic of Macedonia, who was in Barcelona and Istanbul a year ago, was taken to the state hospital because of fever and hepatosplenomegaly. The diagnosis is made with bone marrow biopsy. The patient had previously an aortic coronary bypass transplant. During the stay of the Intensive Care and Therapy Department at the Clinic for Infectious Diseases and Febrile Conditions in Skopje, Hepatitis C virus has been laboratory diagnosed. Unfortunately, the patient ended with death. Conclusion: We hope that with the presentation of this case, we will increase the need for further exploration of geographical changes, epidemiological characteristics and interconnections between leishmania parasites. Keyword: leishmaniasis, protozoa, Hepatitis C 1.INTRODUCTION Visceral leishmaniasis (cala-azar) caused by the protozoal parasite Leishmania donovani, is one of the major causes of worldwide morbidity and mortality (1). Leishmaniasis is an inflammatory, chronic disease that affects the skin, mucous membranes and visceral organs, caused by intracellular parasites that are transmitted by infected sand flies of the genus Flebotomus. The life cycle of Leishmania takes place in two phases, the promastigote which lives extracellularly in the infected phlebotomes and the amastigote, which lives and reproduces intracellularly in the host's reticuloendothelial cells (2). Mammals, including foxes, rodents and dogs are infection reservoirs (3). The amastigotes from Leishmania species have a particular affinity for replication in the liver, spleen, bone marrow and lymph nodes causing fatal lesions. (4). We present a complex case of a 56 year old woman from Skopje, Republic of Macedonia with three independent types of morbidities, as follows: aortic coronary bypass transplant, Hepatitis C and visceral leishmaniasis. 2.CASE REPORT 56-year old woman from Skopje, Republic of Macedonia of Albanian nationality was referred to University Clinic for Infectious Diseases and Febrile conditions in Skopje for management of visceral leishmaniasis. This patient 10 years ago was admitted to the Clinic “Filip II” because of a heart attack. An aortic coronary bypass transplant was made. She regularly went to controls for the examination of cardiac function and control of current therapy. She has been advised on several occasions t

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Elizabeta Zisovska
Date Deposited: 13 May 2019 13:10
Last Modified: 13 May 2019 13:10
URI: http://eprints.ugd.edu.mk/id/eprint/22024

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