Severe renal function impairment in adult patients acutely poisoned with concentrated acetic acid

Chibishev, Andon and Shikole, Aleksandar and Pereska, Zanina and Chibisheva, Vesna and Simonovska, Natasa and Orovchanec, Nikola (2013) Severe renal function impairment in adult patients acutely poisoned with concentrated acetic acid. Archives of Industrial Hygiene and Toxicology, 64. pp. 153-158. ISSN 0004-1254

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Abstract

Acetic acid is a widely used organic acid with corrosive properties that depend on its concentration. If acetic acid is ingested in concentrations above 30 % it may severely damage the upper gastrointestinal tract and cause intravascular haemolysis, which can result in severe kidney and liver disorders and disseminated intravascular coagulation. In this retrospective study, we analysed acetic acid ingestion data collected at the University Clinic for Toxicology of Skopje, Macedonia from 1 January 2002 to 31 December 2011. The analysis included systemic complications, kidney damage, and the outcomes in particular. Over the ten years, 84 patients were reported at the Clinic to have ingested highly concentrated acetic acid. Twenty-eight developed kidney disorders, while the remaining 56 had no complications. Fatal outcome was reported for 11 patients, seven of whom had systemic complications and four severe gastrointestinal complications.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Andon Cibisev
Date Deposited: 12 Mar 2019 09:54
Last Modified: 12 Mar 2019 09:54
URI: http://eprints.ugd.edu.mk/id/eprint/21742

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