Capsaicin and dihydrocapsaicin variability in Capsicum sp. cultivars from Republic of Macedonia, revealed by validated HPLC method

Maksimova, Viktorija and Koleva Gudeva, Liljana and Gulaboski, Rubin and Shishovska, Maja and Arsova-Sarafinovska, Zorica (2017) Capsaicin and dihydrocapsaicin variability in Capsicum sp. cultivars from Republic of Macedonia, revealed by validated HPLC method. Journal of Agriculture and Plant Sciences, JAPS, 15 (1/2). pp. 89-96. ISSN 2545-4447

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Abstract

Capsaicinoids are large group of analogues synthesized in hot peppers, Capsicum annuum L. as secondary metabolites. Hot peppers are widely used in nutrition but their exploitation could be increased because
of capsaicin’s pharmacological properties, as analgesic, antidiabetic, hypolipidemic and antitumor agent.
Therefore, the aim of this study was to determine capsaicinoids (capsaicin and dihydrocapsaicin) in ethanolic
extracts obtained from the fruits of 15 different genotypes and evaluate their variability. Quantification of
capsaicinoids extracted from peppers cultivated in Republic of Macedonia has been performed by a validated
simple and sensitive HPLC method. Although capsaicin has been known as the highest represent in the group
of capsaicinoids, it was found in this study that genotypes that contain higher amount of total capsaicinoids
has even higher content of dihydrocapsaicin than capsaicin. The ratio of capsaicinoids in the extracts obtained
by Soxlet method was similar to that of extracts obtained by maceration. In the extract obtained from
vezena dolga,capsaicin has been represented with 42.80% and 45.99% dihydrocapsaicin. Their content in the extract
from dzinki was 31.44% and 45.41% for capsaicin and dihydrocapsaicin, respectively, and in the extract from
vezena kusa, capsaicin has been represented by 28.85% and dihydrocapsaicin by 48.82%. Since, the biological
activity of dihydrocapsaicin has not been clearly reported; these data can be very useful for breeders of hot
peppers aimed in further extraction of capsaicin for medicinal purposes.

Item Type:	Article
Subjects:	Natural sciences > Chemical sciences
Divisions:	Faculty of Medical Science
Depositing User:	Viktorija Maksimova
Date Deposited:	22 Jan 2018 11:58
Last Modified:	22 Jan 2018 11:58
URI:	https://eprints.ugd.edu.mk/id/eprint/19004

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