Evaluation of genotoxicological effect on ionizing radiation to medical occupationally exposed workers

Velickova, Nevenka and Milev, Mishko (2017) Evaluation of genotoxicological effect on ionizing radiation to medical occupationally exposed workers. In: 3 Hrvatski kongres zdravstvene ekologije s medzunarodnim sudjelovanjem, 24-27 Apr 2017, Tuhelj, Croatia.

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Abstract

Background: Medical personnel are often occupationally exposed to chronic ionizing radiation (IR). It is known that IR may have damaging effects on chromosomes and genes. The aim of this study was to evaluate the genotoxicity of IR on medical personnel using the micronucleus assay (cytokinesis-block MN) as genotoxicity method and to determine the human health risk. Methods: In this study we observed that medical personnel (with long time of exposer of IR) have a increasing the incidence of micronuclei (MNi) (average 16 MN per 1000 binuclear lymphocites). Results: According to our results we concluded that all of them have a risk of professional disease and cancer. Conclusion: This study has a practical importance because it indicates the necessity of introducing a permanent genotoxicological and other type of monitoring of medical personnel exposed to IR and suggests the need of application of different cytogenetic methods and genotoxicological test (like MN assay) that can confirm the chromosome rearrangements.

Item Type: Conference or Workshop Item (Lecture)
Subjects: Medical and Health Sciences > Basic medicine
Divisions: Faculty of Medical Science
Depositing User: Nevenka Velickova
Date Deposited: 15 May 2017 09:14
Last Modified: 15 May 2017 09:14
URI: http://eprints.ugd.edu.mk/id/eprint/17763

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