Off-label and unlicensed use of medicines in Macedonian neonatal wards

Zisovska, Elizabeta and Slaveska-Raicki, Renata and Glavas Dodov, Marija and Simonovska Crcarevska, Maja and Coshi, Blerina and Tonic Ribarska, Jamina (2016) Off-label and unlicensed use of medicines in Macedonian neonatal wards. International Journal of Pharmaceutics, 511 (2). pp. 1140-1141. ISSN 0378-5173

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Despite all efforts to improve the use of licensed on-label medicines, there is still high percentage of off-label and unlicensed use of medicines in neonatal therapy. Therefore, the aim of this study was to investigate, analyze and present the extent and manner of use of medicines that are either outside the terms of their product license (off label), or are not licensed (unlicensed) within the neonatal therapeutic areas. This study was designed as a pilot cohort study, prospectively conducted in, and involving all newborns admitted to the Department of Neonatology, Republic of Macedonia. The results have shown high percentage of off-label use in preterm newborns, compared with term newborns, especially use out of age and out of indication.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Elizabeta Zisovska
Date Deposited: 27 Mar 2017 11:25
Last Modified: 27 Mar 2017 11:25

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