Approaches in evaluation of freeze-dried antibody conjugates

Smilkov, Katarina and Gjorgieva Ackova, Darinka and Makreski, Petre and Gjorgoski, Icko and Janevik-Ivanovska, Emilija (2016) Approaches in evaluation of freeze-dried antibody conjugates. Macedonian Pharmaceutical Bulletin, 62. ISSN 1409-8695

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Abstract

The presented experience was in freeze-drying of monoclonal antibody – rituximab, conjugated with three types of bifunctional chelating agents, p-SCN-Bn-DOTA, p-SCN-Bn-DTPA, and 1B4M-DTPA, and evaluation of possible changes in post-freeze-drying phase, using SDS-PAGE electrophoresis, FT-IR and Raman spectroscopy techniques.

Item Type: Article
Subjects: Natural sciences > Biological sciences
Natural sciences > Chemical sciences
Medical and Health Sciences > Health biotechnology
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Katarina Smilkov
Date Deposited: 31 Jan 2017 10:23
Last Modified: 31 Jan 2017 10:23
URI: http://eprints.ugd.edu.mk/id/eprint/17090

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