Traditional versus new oral anticoagulants in clinical practice of oral surgery

Dimova, Cena and Popovska, Lidija and Zdravkovska, Milka and Popovska, Mirjana and Zlatanovska, Katerina (2016) Traditional versus new oral anticoagulants in clinical practice of oral surgery. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7 (5). pp. 170-176. ISSN 0975-8585

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The oral surgeons are frequently asked to manage patients who are receiving oral anticoagulants. The aim of treatment is to minimize the risk of hemorrhage while continuing to protect the patient against thromboembolism formation. The ordinary treatment includes the interruption of anticoagulant therapy before oral surgery interventions to prevent hemorrhage. Aim of this study is to review the evidence of different therapy approach, to highlight the areas of major concern, and to suggest specific oral surgery treatment for patients on new oral anticoagulants. A Medline and extensive hand search were performed on English-language publications beginning in 1960 till now. Several evolving clinical practices in the last years have been detected: anticoagulants are generally not discontinued; oral surgery is performed despite laboratory values showing significant bleeding tendency; new effective local hemostatic modalities are used to prevent bleeding. It is too early to make comments on how to choose among the different new anticoagulants, not only because no head-to-head comparative study has been yet performed, but also because the currently available data are insufficient to make a meaningful choice possible. Keywords: oral surgery, oral anticoagulants, low-molecular heparin, bleeding.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Cena Dimova
Date Deposited: 14 Sep 2016 07:51
Last Modified: 14 Sep 2016 07:51

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