Crystal Structure and Packing Analysis of Nitrofurantoin N,N-dimethylformamide Solvate

Cvetkovski, Aleksandar and Ferretti, Valeria (2016) Crystal Structure and Packing Analysis of Nitrofurantoin N,N-dimethylformamide Solvate. Crystallography Reports, 4. ISSN 1063-7745 (Print)/1562-689X (Online) (In Press)

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Official URL: http://link.springer.com/journal/11445

Abstract

Abstract – The N, N’-dimethylformamide solvated crystal of the drug nitrofurantoin has been prepared and analysed by single-crystal X-ray diffraction. The two co-crystallized molecules, in the 1:1 stoichiometric ratio, are linked by a medium/strong N−H···O hydrogen bond (N···O is 2.759 (3) Å) and a weaker C−H···O interaction to form isolated supramolecular adducts, that in turn are packed into the lattice framework mainly through C−H···O hydrogen bonds. Two-dimensional fingerprint plots of Hirshfeld surfaces are used to visualize, analyze and compare intermolecular interactions found in the title compound and in similar structures.

Item Type: Article
Subjects: Natural sciences > Chemical sciences
Divisions: Faculty of Medical Science
Depositing User: Aleksandar Cvetkovski
Date Deposited: 01 Jun 2016 10:02
Last Modified: 01 Jun 2016 10:02
URI: http://eprints.ugd.edu.mk/id/eprint/15679

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