Prevention from transfusion transmissive diseases in the regional center for transfusion medicine in Stip, Republic of Macedonia for the period 2009-2010

Kamcev, Nikola and Kamceva, Gordana and Velickova, Nevenka (2011) Prevention from transfusion transmissive diseases in the regional center for transfusion medicine in Stip, Republic of Macedonia for the period 2009-2010. Vox Sanguinis, 101 (2 ). ISSN 1423-0410

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Abstract

Introduction: Blood transfusion is a transplantation of fluid tissue or an introduction of human biological material that needs to survive in the donor organism and to play important biological functions. During the blood and blood products transfusion, it is possible to transmit many transfusion transmissive diseases, which increases the need of securing safe blood transfusion. Objective: To present the procedures and measures taken in order to prevent the transmission of transfusion transmissive diseases in the blood and blood products donors at the Clinical Hospital in Stip. Materials and methods: Each blood unit was mandatory tested for HBSAG, anti- HCV, anti-HIV and Treponema pallidum antibodies at the Regional center for transfusion medicine. The testing was done with the ELISA technique by using the Dade Berhing BEP 200 instrument and the tests from Siemens and Ortho for anti-HCV. The confirmation tests were done at the Institute of Transfusion Medicine in the capital Skopje. Results: In total, 6067 blood samples were tested. The presence of HBAGS was detected in 81 sample (1.33%), anti-HCV in 19 (0.313%), anti-HIV in one (0,016%) and Treponema pallidum antibodies in 5 samples (0.082%). Discussion and conclusion: In order to achieve high level of security of the transfusion blood and blood products it is essential to use highly specific and sensitive tests, modern equipment, well trained health personnel and sufficient financial resources allocated specifically for that aim.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Health sciences
Divisions: Faculty of Medical Science
Depositing User: Nevenka Velickova
Date Deposited: 26 Nov 2012 13:43
Last Modified: 27 Nov 2012 07:18
URI: http://eprints.ugd.edu.mk/id/eprint/1486

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