Use of Framingham model for identifying type 2 diabetes patients for primary prevention of coronary artery disease with statin treatment

Georgiev, Antonio and Smokovski, Ivica and Pavlovska, Kristina and Georgieva, Daniela (2009) Use of Framingham model for identifying type 2 diabetes patients for primary prevention of coronary artery disease with statin treatment. Medicus, 12 (2). pp. 18-21. ISSN 1409-6366

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Abstract

Objective: To determine the number of type 2 diabetic patients identified for primary prevention of Coronary Artery Disease (CAD) with statins by Framingham model for calculation of 10-year CAD absolute risk. Material and methods: Observational, cross-sectional study including 516 type 2 diabetic patients with no arterial disease (CAD, cerebrovascular disease or peripheral arterial disease), no prior hypolipaemic treatment, aged 30-65 years, receiving insulin treatment for 6 months. Patients were identified for primary prevention of CAD with statins if 10-year CAD absolute risk was higher than 15% as assessed by Framingham model and total cholesterol higher than 5.0 mmol/l. Results: Out of 516 patients, mean 10-year absolute risk for CAD as assessed by Framingham model was 16.8 ± 8.6%, and 232 patients (45.0%) were identified with 10-year CAD absolute risk >15% and total cholesterol >5.0 mmol/l. Conclusion: Use of Framingham model identifies cosiderable number of type 2 diabetic patients with no primary prevention in whom such pevention of CAD with statins is required, having both clinical and health economics implications. Key words: Framingham, diabetes type 2, primary

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Ivica Smokovski
Date Deposited: 28 Dec 2015 11:33
Last Modified: 28 Dec 2015 11:33
URI: http://eprints.ugd.edu.mk/id/eprint/14620

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