Reduction of cardiovascular risk in type 2 diabetes patients as assessed by SCORE system 6 months after initiation of insulin treatment

Georgiev, Antonio and Smokovski, Ivica and Pavlovska, Krisitina (2008) Reduction of cardiovascular risk in type 2 diabetes patients as assessed by SCORE system 6 months after initiation of insulin treatment. Macedonian Medical Review, 62 (3). pp. 45-48. ISSN 0025-1097

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Abstract

Aim: To assess the difference in 10-year risk of fatal cardiovascular disease (CVD) in type 2 diabetes mellitus (DM) patients without CVD and microalbuminuria not using statin treatment by the system for risk assessment SCORE prior to and 6 months after initiation of insulin treatment, and to identify the patient distribution according to the level of risk and number of patients requiring statin treatment after 6 months of insulin treatment. Materials and methods: Retrospective, observational, cross-sectional study of 516 patients with DM type 2 without CVD and microalbuminuria not using statin treatment prior to and 6 months after initiation of insulin treatment. Results: Mean 10-year risk of fatal CVD assessed by SCORE system after insulin treatment was significantly reduced compared to the risk before insulin treatment (12.3 ± 10.5 vs. 13.5 ± 11.4%, p<0.001). Increased risk (≥5%) was identified in the majority of patients (n=465; 90.1%), and 382 patients were identified with both increased risk (SCORE ≥5%) and total cholesterol ≥5 mmol/l after 6 months of insulin treatment. Conclusion: Use of SCORE system in the cohort of type 2 DM patients without CVD and microalbuminuria not using statin treatment, identified reduction of mean 10-year risk of fatal CVD after 6 months of insulin treatment and confirmed the need of CVD primary prevention with statin treatment in 362 patients (26.0%) of the studied cohort.

Item Type: Article
Subjects: Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Ivica Smokovski
Date Deposited: 21 Dec 2015 10:15
Last Modified: 21 Dec 2015 10:15
URI: http://eprints.ugd.edu.mk/id/eprint/14613

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