Survival in triple negative metastatic breast carcinoma-case report

Serafimov, Aleksandar and Karakolevska Ilova, Marija and Simeonovska Joveva, Elena (2015) Survival in triple negative metastatic breast carcinoma-case report. Annals of Applied Bio-Sciences, 2 (4). pp. 72-74. ISSN 2349-6991


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Breast cancer is the most common non-skin malignancy in women, the second most common cause of cancer death, and the main cause of death in women ages 45 to 55 years. An estimated 1 million cases of breast cancer are diagnosed annually worldwide. Approximately 5-10% of patients with breast cancer have distant metastases at first presentation. The patient came to the Clinic of oncology and radiotherapy in March 2005 for further treatment with the diagnosis: Carcinoma metastaticum vertebrae lumbosacralis. Initial treatment was included 6 cycles of chemotherapy, bisphosphonate therapy and realized radiotherapy. Tumor markers at the end of treatment: CEA 238; CA15-3: 19.6. After that a radical mastectomy of the left breast with dissection of left axilla was conducted and pathological analysis showed poorly differentiated ductal invasive carcinoma (grade 3 according to Nottingham Histologic Score) with immunohistochemistry findings: HER: negative, ER: negative, PR: negative or Triple negative breast cancer (TNBC).

Item Type: Article
Additional Information: Annals of Applied Bio-Sciences (AABS) is an international, fast double-blind peer-reviewed, indexed, open access, online and print multidisciplinary journal with high impact factor (2.9254) and IC value (56.90), published by 'Pacific group of e-Journals' (PaGe), an ISO 9001:2008 Certified academic publishing house, with a quick post-acceptance online publication.
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Aleksandar Serafimov
Date Deposited: 27 Oct 2015 13:59
Last Modified: 27 Oct 2015 13:59

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