New Trends in Biomonitoring: Application of RAPD-PCR and Plant Model Systems to Genetic Ecotoxicology

Gjorgieva, Darinka and Kadifkova-Panovska, Tatjana and Mitrev, Sasa and Kovacevik, Biljana and Arsov, Emilija (2011) New Trends in Biomonitoring: Application of RAPD-PCR and Plant Model Systems to Genetic Ecotoxicology. In: Fifth Congress of Pharmacy of Macedonia with International Participation, 21 – 25.09.2011, Ohrid, Macedonia.

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Abstract

Biomonitoring should act as an early warning system providing information about the seriousness of the pollution by sensitive assays, especially for existing potential genotoxic problem assessment, since most polluting substances have shown genotoxic effect. A further consideration is that changes in the DNA fingerprints obtained may be used to identify target genes for particular genotoxic agents. Characterisation of these DNA molecules using DNA sequencing techniques may enable the identification of specific sequences that are hotspots for mutation by particular agents; this will open up possibilities of designing specific assays for detection of specific agents and may help explain the presence in the genome of preferential mutation points.

Item Type: Conference or Workshop Item (Speech)
Subjects: Natural sciences > Biological sciences
Medical and Health Sciences > Other medical sciences
Natural sciences > Other natural sciences
Divisions: Faculty of Medical Science
Depositing User: Darinka Gjorgieva Ackova
Date Deposited: 19 Nov 2012 15:30
Last Modified: 23 Dec 2016 13:19
URI: http://eprints.ugd.edu.mk/id/eprint/1346

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