Gulaboski, Rubin and Lovrić, Milivoj and Mirceski, Valentin and Bogeski, Ivan and Hoth, Markus (2008) A new rapid and simple method to determine the kinetics of electrode reactions of biologically relevant compounds from the halfpeak width of the squarewave voltammograms. Biophysical Chemistry, 138 (3). pp. 130137. ISSN 03014622

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Abstract
A new method is introduced to determine the kinetic parameters of electron transfer reactions of biologically important compounds, based on the measurements of the halfpeak width (ΔEp/2) of the squarewave voltammograms. A simple surface (diffusionless) redox reaction, and a simple electrode reaction occurring from dissolved state are considered as model systems. In the region of quasireversible electron transfer, the halfpeak widths of theoretical squarewave voltammograms are linear functions of the logarithm of the dimensionless kinetic parameter ln(K) that characterizes the rate of the electron transfer reaction. The dimensionless kinetic parameter K is defined as K=ks(fD)−0.5 for the redox reaction taking place from dissolved state, whereas for the surface redox reaction K is defined as K=ks/f (ks is the standard rate constant of electron transfer, f is the SW frequency, and D is the diffusion coefficient). A set of linear regression equations for the dependences ΔEp/2 vs. ln(K) are derived, which can be used for rapid and precise determination of the chargetransfer kinetic parameters. The estimated values for the standard rate constants of various biologically relevant redox systems using this approach are in very good agreement with the experimental values determined by other squarewave voltammetric methods. The squarewave voltammetric halfpeak width method can be used as a simple and reliable alternative to other voltammetric methods developed for the kinetic characterization of electron transfer rates.
Item Type:  Article 

Uncontrolled Keywords:  squarewave voltammetry, mathematical modeling, kinetic parameters, halfpeak width, standard rate constant of electron transfer, electron transfer coefficient, amperometry 
Subjects:  Natural sciences > Chemical sciences 
Divisions:  Faculty of Agriculture 
Depositing User:  Rubin Gulaboski 
Date Deposited:  31 Oct 2012 10:26 
Last Modified:  31 Oct 2012 10:26 
URI:  http://eprints.ugd.edu.mk/id/eprint/134 
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