Perspectives on regeneration of alveolar bone defects

Efremov, Ljupco and Kanjevac, Tatjana and Curic, Dusica and Bosnakovski, Darko (2014) Perspectives on regeneration of alveolar bone defects. Serbian Journal of Experimental and Clinical Research, 14 (4). pp. 14-153.

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Abstract

Bone atrophy of the alveolar process is an important parameter in patients undergoing dental implants. There are several methods for preserving the alveolar process, with the autologous bone graft as the gold standard. Other approaches include the use of allografts, xenografts and synthetic bone grafts. In recent years, the use of stem cells has increased in importance. Th e most common type of stem cells used are mesenchymal stem cells from various sources, including bone marrow, adipose tissue and dental pulp. The discovery of induced pluripotent stem cells and the continued research on embryonic stem cells open new possibilities in this field. However, further research is needed to optimise protocols for isolation, diff erentiation and transplantation of cells with or without appropriate scaff olds, and to determine the correct clinical and therapeutic implications.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Medical and Health Sciences > Health biotechnology
Divisions: Faculty of Medical Science
Depositing User: Darko Bosnakovski
Date Deposited: 04 Feb 2015 11:19
Last Modified: 04 Feb 2015 11:19
URI: http://eprints.ugd.edu.mk/id/eprint/12343

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