Diagnostic procedures, therapy and complications of haemophilia

Naumovska, Marija and Velickova, Nevenka and Kamcev, Nikola and Milev, Mishko (2014) Diagnostic procedures, therapy and complications of haemophilia. International Scientific Journal, Science & Technologies, 4 (1). pp. 101-106. ISSN 1314-4111


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Introduction: Defects in blood coagulation can be congenital or acquired. Haemophilia belongs to the congenital (hereditary) coagulopathies.It is inherited recessively by a mutant gene located on the X-chromosome, therefore it affects only men. There are two common types of haemophilia, A and B. Aim of this researche is to trace the representation of haemophilia in the general population, to follow the clinical course, diagnostic procedures, necessary therapy, complications, the role of the laboratory analyst in constructing precise and proper analysis. Results: We are followed three cases of haemophilia, recorded in transfusion department at the Clinical Center in Macedonia. For the purpose of this paper work are allocated three people, two with haemophilia A, one child and one adult person and one person with haemophilia B, all male. In all these cases, therapy is preventive and receive appropriate according to age and needs. Their dose increases in case of injuries or extensive bleeding. Conclusion: Early prophylactic use of clotting factors with severe haemophilia is gaining acceptance as a way to prevent pain and morbidity associated with bleeding disorders. Treatment of severe haemophilia A or B consists of administration of plasma-derived or recombinant clotting factor concentrates.

Item Type: Article
Subjects: Medical and Health Sciences > Basic medicine
Divisions: Faculty of Medical Science
Depositing User: Nevenka Velickova
Date Deposited: 25 Nov 2014 14:25
Last Modified: 13 Mar 2015 10:23
URI: http://eprints.ugd.edu.mk/id/eprint/11435

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