Orthostatic Reactivity in Patients With Diabetic Neuropathy

Lubenova, Daniela and Titianova, Ekaterina and Vasileva, Dance (2014) Orthostatic Reactivity in Patients With Diabetic Neuropathy. Macedonian Journal of Medical Sciences, 7 (2). pp. 244-248. ISSN 1857-5773

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Abstract

The purpose of the study was to assess the effect of a structured physical therapy (PT) programme on the orthostatic reactivity in patients with diabetic neuropathy (DNP). The study was performed in 90 patients with DNP (34 male and 56 female, mean age 60.8±7.8 years) of lower extremities. The orthostatic autoregulation was evaluated using an active orthostatic test. The arterial blood pressure and the heart rate were determined after 10 minutes of rest in lying position before and after 1, 5 and 10 minutes of active standing. All patients had therapy with alpha-lipoic acid and a structured intensive 10 days PT program, later continued as a home exercise programme. The orthostatic autoregulation was evaluated three times – at the start of the study, at day 10 and at 6 weeks after the beginning of PT. The classification of Thulesius was used to divide the patients into 3 groups according to the type of their orthostatic reactivity. At the start of the study a normotonic orthostatic reactivity (NOR) was observed in 32 patients. Abnormal sympathicotonic type of orthostatic reactivity (SOR) was found in 18 patients and asympaticotonic type of orthostatic reactivity (AOR) was established in the remaining 40 patients. After the PT treatment a significant improvement of the orthostatic autoregulation in the groups with SOR and AOR was found – NOR was observed in 66 patients with DNP (80.3%) at 6 weeks after the start of PT. The applied structured PT, later continued as a home exercise programme, significantly improved the orthostatic reactivity in patients with orthostatic dysregulation due to DNP. Author Keywords: Exercise Therapy, Orthostatic Tolerance, Physical Therapy, Type II Diabetes

Item Type: Article
Additional Information: None of the authors or their institution has received any commercial financial support related to this study. This work was partly supported from the National Sports Academy “V. Levski” - Sofia, Bulgaria.
Uncontrolled Keywords: Exercise Therapy, Orthostatic Tolerance, Physical Therapy, Type II Diabetes
Subjects: Medical and Health Sciences > Clinical medicine
Medical and Health Sciences > Health sciences
Medical and Health Sciences > Other medical sciences
Divisions: Faculty of Medical Science
Depositing User: Dance Vasileva
Date Deposited: 25 Aug 2014 12:09
Last Modified: 22 Oct 2014 13:29
URI: http://eprints.ugd.edu.mk/id/eprint/10719

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