Heart failure and early hospital mortality in patients with acute myocardial infarction with ST-segment elevation

Kamceva, Gordana and Kamcev, Nikola and Velkoska Nakova, Valentina and Vavlukis, Marija and Kedev, Sasko (2012) Heart failure and early hospital mortality in patients with acute myocardial infarction with ST-segment elevation. In: Heart Failure Congres, 19-22 May, Belgrade, Serbia.

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Abstract

Introduction: Coronary artery disease, with its predominantly recognized acute clinical manifestation - Acute myocardial infarction remains the leading cause of death in developed, but even more in transition and developing countries. In 2000, cardiovascular diseases are the cause of death for> 4 million people in Europe and myocardial infarction predicts that 2020 will be the main cause of death worldwide. Purpose: To monitor early hospital morbidity, intra-hospital complications and mortality in patients with acute myocardial infarction with ST-segment elevation (STEMI) treated without reperfusion therapy, in patients who receive pharmacological reperfusion therapy and in patients treated with mechanical reperfusion therapy . Methods: The study included patients diagnosed with STEMI within three years from the eastern region of the Republic of Macedonia. Patients were divided into three groups: Group 1 - patients treated without reperfusion therapy, Group 2 - patients who receive pharmacological reperfusion therapy Group 3 - patients who were treated with mechanical reperfusion therapy (PKI). Early hospital morbidity, intra-hospital complications and mortality were observed in all three groups. Results: From 2008 to 2010 registered a total of 543 patients with STEMI. In 2008 registered 156 (28.7%) patients, 196 (36.1%) in 2009, and 191 in 2010 (35.2%) person. Of the total 543 patients, 161 (29.7%) were women and 382 (70.3%) were male, with average age of 60,43  11,76 years. Most patients with STEMI - 320 (58.93%) were treated conservatively. With pharmacological reperfusion therapy were treated 17 (3.13%) patients, and with mechanical reperfusion therapy (PKI) were treated 206 (37.94%) patients. In terms of early morbidity and intra-hospital complications, the most recorded complications were rhythm disorders and conduction - in 34 (6.26%), mechanical complications in 25 (4.60%) and haemodynamic complications - in 25 (4.60%) patients. There is a correlation between the kind of treatment and hospital morbidity, it is more established in patients on conservative treatment ( 2 test = 58,33 df = 24 p = 0,00011). The type of morbidity, heart failure carries the highest hospital mortality, followed by malignant rhythm disorders and conduction. ( 2 test = 56,98 df = 1 p = 0,00011) Conclusion: The conservative treatment of patients with STEMI carries a higher risk of developing intra-hospital complications. Haemodynamic complications, which include heart failure, by frequency is on the third place. However, heart failure carries the highest hospital mortality. Key words: heart failure, acute myocardial infarction with ST-segment elevation, intrahospital complications, hospital morbidity and hospital mortality.

Item Type: Conference or Workshop Item (Poster)
Subjects: Medical and Health Sciences > Clinical medicine
Divisions: Faculty of Medical Science
Depositing User: Gordana Kamceva
Date Deposited: 27 Jun 2014 13:05
Last Modified: 27 Jun 2014 13:05
URI: http://eprints.ugd.edu.mk/id/eprint/10236

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